We investigated how vitamin B6 supports heart recovery after heart attacks by promoting new blood vessel growth, known as angiogenesis. In laboratory tests, vitamin B6 improved cell migration and tubule formation, vital for forming new blood vessels.
Remarkably, long-term vitamin B6 supplementation showed significant improvements in heart function and reduced inflammation in mice following heart attacks. This suggests that vitamin B6 could be a beneficial aid for heart recovery, harnessing a specific pathway involving a protein called AMPK.
Read More
8
Folate slows artery thickness increase
Serum folate levels, but not vitamin B12, are associated with slower progression in carotid intima-media thickness in a population exposed to mandatory folic acid fortification.
We examined the link between folate and vitamin B12 levels and changes in carotid intima-media thickness (cIMT), a marker of early heart disease, over eight years in a group of 5061 adults in Brazil.
Our results suggest that higher serum folate levels are associated with a slower increase in cIMT, indicating a potential protective effect against heart disease.
However, no such benefit was observed with vitamin B12 levels. This implies that while folate may play a role in cardiovascular health, vitamin B12 might not have the same impact.
Read More
8
Gene-nutrient interactions and hypertension
Genome-Wide Approach of Gene-Nutrient Intake Interaction Study for Essential Hypertension in a Large Korean Cohort (KoGES).
We explored how specific gene-nutrient interactions affect high blood pressure using data from the Korean Genome and Epidemiology Study, which included over 50,000 participants.
Our findings revealed that individuals with a certain genetic variant showed a lower risk of hypertension when consuming higher amounts of dietary iron and vitamin B6.
This suggests that for some individuals, adjusting their diet could help mitigate hypertension risks.
However, further research is needed to confirm these results across different populations to ensure wider applicability.
Read More
Most Useful Reviews
9
Reduced migraine symptoms
18 people found this helpful
Trims my migraine attacks significantly. I have a classic migraine and was sceptical about B-Complex being effective, but the results were striking: my seizure frequency dropped. When I stopped taking it, my attacks increased. With this complex, I consume one pack of triptans a month instead of six to seven.
Read More
7.5
Improved energy levels
10 people found this helpful
I'm pleased to find this in capsule form by Solgar, which is known for quality. Since taking these vitamins, my constant fatigue has disappeared, my sleep has improved, and my hair no longer falls out. I feel my heart is healthier, and skin irritations have vanished. These vitamins are essential for my body during stressful times.
Read More
7.5
Enhanced mood stability
3 people found this helpful
After starting this complex, my joint pain and depressive feelings have lessened. I noticed changes within a week, feeling more energetic and stable emotionally. This Solgar vitamin B supports my cardiovascular health and nervous system, and I appreciate its mild taste and high quality.
We investigated how vitamin B6 supports heart recovery after heart attacks by promoting new blood vessel growth, known as angiogenesis. In laboratory tests, vitamin B6 improved cell migration and tubule formation, vital for forming new blood vessels.
Remarkably, long-term vitamin B6 supplementation showed significant improvements in heart function and reduced inflammation in mice following heart attacks. This suggests that vitamin B6 could be a beneficial aid for heart recovery, harnessing a specific pathway involving a protein called AMPK.
Read More
8
Gene-nutrient interactions and hypertension
Genome-Wide Approach of Gene-Nutrient Intake Interaction Study for Essential Hypertension in a Large Korean Cohort (KoGES).
We explored how specific gene-nutrient interactions affect high blood pressure using data from the Korean Genome and Epidemiology Study, which included over 50,000 participants.
Our findings revealed that individuals with a certain genetic variant showed a lower risk of hypertension when consuming higher amounts of dietary iron and vitamin B6.
This suggests that for some individuals, adjusting their diet could help mitigate hypertension risks.
However, further research is needed to confirm these results across different populations to ensure wider applicability.
Read More
8
Folate slows artery thickness increase
Serum folate levels, but not vitamin B12, are associated with slower progression in carotid intima-media thickness in a population exposed to mandatory folic acid fortification.
We examined the link between folate and vitamin B12 levels and changes in carotid intima-media thickness (cIMT), a marker of early heart disease, over eight years in a group of 5061 adults in Brazil.
Our results suggest that higher serum folate levels are associated with a slower increase in cIMT, indicating a potential protective effect against heart disease.
However, no such benefit was observed with vitamin B12 levels. This implies that while folate may play a role in cardiovascular health, vitamin B12 might not have the same impact.
Read More
8
Niacin intake lowers mortality risks
Association of dietary niacin intake with all-cause and cardiovascular mortality: National Health and Nutrition Examination Survey (NHANES) 2003-2018.
We looked into how dietary niacin might affect mortality rates, particularly for cardiovascular disease. Analyzing data from nearly 27,000 U.S. adults over about nine years, we found that those with the highest niacin intake had a significantly lower risk of dying from any cause, as well as from heart-related issues.
Interestingly, this protective effect was more robust among those without diabetes, suggesting that niacin's benefits can vary by health condition. Our findings highlight the potential role of diet in supporting heart health.
Read More
7
Vitamin B influence on hypertension
Relationship between blood pressure variability and vitamin B level in essential hypertension.
We investigated the connection between blood pressure variability (BPV) and vitamin B6 and B12 levels in individuals with essential hypertension. Our study involved 100 patients with hypertension and a control group of 100 healthy individuals.
We found that patients with hypertension had significantly lower levels of these B vitamins compared to the healthy group. Additionally, those with higher B vitamin levels exhibited reduced BPV.
This suggests that Vitamin B6 and B12 may influence blood pressure control, providing insights into hypertension management strategies.
Read More
User Reviews
USERS' SCORE
Good
Based on 11 Reviews
8.3
All Reviews
Positive Reviews
Negative Reviews
9
Reduced migraine symptoms
18 people found this helpful
Trims my migraine attacks significantly. I have a classic migraine and was sceptical about B-Complex being effective, but the results were striking: my seizure frequency dropped. When I stopped taking it, my attacks increased. With this complex, I consume one pack of triptans a month instead of six to seven.
Read More
7.5
Improved energy levels
10 people found this helpful
I'm pleased to find this in capsule form by Solgar, which is known for quality. Since taking these vitamins, my constant fatigue has disappeared, my sleep has improved, and my hair no longer falls out. I feel my heart is healthier, and skin irritations have vanished. These vitamins are essential for my body during stressful times.
Read More
7.5
Enhanced mood stability
3 people found this helpful
After starting this complex, my joint pain and depressive feelings have lessened. I noticed changes within a week, feeling more energetic and stable emotionally. This Solgar vitamin B supports my cardiovascular health and nervous system, and I appreciate its mild taste and high quality.
Read More
8
Effective stress relief
1 people found this helpful
This is a high-quality complex supporting cardiovascular health and energy. It effectively relieves irritability and stress. One capsule with meals suffices, and despite their water-soluble nature, I notice improved appetite and skin condition without any adverse effects on my body.
Read More
7.5
Boosted immune system
1 people found this helpful
B vitamins are vital for energy, emotional health, and multiple bodily functions including combatting cardiovascular disease. Insufficient B vitamins can lead to fatigue and poor memory. The synergy of this complex is effective for enhancing overall health.
Cardiovascular disease (CVD) is a broad term that encompasses a range of heart and blood vessel disorders. This can include conditions such as coronary artery disease, which leads to heart attacks; cerebrovascular disease that results in strokes; and peripheral artery disease affecting blood flow to the limbs. The key risk factors for CVD often include high blood pressure, high cholesterol, obesity, smoking, a sedentary lifestyle, and diabetes. By identifying and managing these risk factors, individuals can significantly reduce their likelihood of developing cardiovascular problems.
Prevention and treatment strategies often involve lifestyle modifications such as adopting a heart-healthy diet rich in fruits, vegetables, whole grains, and lean proteins, alongside engaging in regular physical activity. In some cases, medications might be necessary to control blood pressure or cholesterol levels. Regular check-ups with a healthcare provider are essential for monitoring heart health, especially for individuals with a family history of CVD. Understanding the signs and symptoms of cardiovascular issues—like chest pain, shortness of breath, or fatigue—can help in seeking timely medical attention, ultimately leading to better outcomes.
Vitamin B Complex refers to a group of water-soluble vitamins that play important roles in cell metabolism and overall health. This group typically includes eight essential vitamins: B1 (thiamine), B2 (riboflavin), B3 (niacin), B5 (pantothenic acid), B6 (pyridoxine), B7 (biotin), B9 (folate), and B12 (cobalamin). Each of these vitamins contributes uniquely to various bodily functions, such as energy production, red blood cell formation, and nervous system function. For instance, B12 and folate are crucial in preventing anemia, while B6 is vital for brain development and function.
Many people can obtain their daily requirements of B vitamins through a balanced diet that includes whole grains, meats, eggs, nuts, leafy greens, and dairy products. However, certain groups—like vegetarians, pregnant women, and older adults—may benefit from supplementation to meet their nutritional needs. It's important to consult with a healthcare professional before starting any supplement regimen, as excessive intake of certain B vitamins can lead to adverse effects. Overall, ensuring adequate intake of Vitamin B Complex is vital for maintaining energy levels and supporting overall health.
Based on user reviews, the timeline for seeing results from B-Complex vitamins can vary, but many users report noticing changes within a week to a month of starting supplementation. For instance, one user mentioned feeling more energetic and stable emotionally just a week after incorporating the vitamins into their routine Read Review. Others have highlighted improvements in various aspects of health, including fatigue reduction and better cardiovascular health, although specific timelines were not detailed Read ReviewRead Review.
While most experiences indicate relatively quick benefits, individual results may differ based on personal health conditions and lifestyle factors. As a reference, users have reported an overall improvement in energy levels, support for cardiovascular health, and stress management—factors that may take a longer time to stabilize effectively, potentially ranging from several weeks to a couple of months Read Review. For best results, consistency in taking the supplement alongside a balanced diet may enhance efficacy.
Recent scientific research suggests that certain B vitamins, particularly Vitamin B6 and folate, may have beneficial effects on cardiovascular health. A study found that patients with hypertension had lower levels of Vitamin B6 and B12, and higher levels of these vitamins correlated with reduced blood pressure variability [1]. Moreover, Vitamin B6 has shown promise in enhancing heart recovery post-heart attack by promoting new blood vessel growth and improving heart function in animal studies [2].
On the other hand, folate seems to be linked to a slower increase in carotid intima-media thickness, which is an early marker for heart disease [4]. This presents folate as a potentially protective factor against heart disease, while the effects of Vitamin B12 may be less significant. Additionally, dietary niacin has been associated with reduced mortality rates from cardiovascular diseases, particularly among individuals without diabetes [5]. Overall, these studies highlight the potential role of specific vitamins in cardiovascular health, but more research is necessary to fully understand their impacts and applications.
Based on user reviews, many individuals have reported significant improvements in various symptoms after starting B-Complex vitamins. One user noted a remarkable decrease in migraine attacks, citing a reduction in seizure frequency and requiring far fewer triptans each month (Read Review). Another reviewer experienced a complete disappearance of fatigue and improved sleep quality, alongside benefits such as healthier hair and skin irritations vanishing (Read Review). Users also reported enhancements in emotional stability, energy levels, and joint pain relief, with some feeling these changes as quickly as a week into supplementation (Read Review).
Additionally, reviews indicate that taking B-Complex vitamins can aid in stress management and cardiovascular health. Users have expressed greater resilience to stress and improved overall support for their cardiovascular and nervous systems (Read Review). While the results can vary from person to person, the consensus is that B-Complex vitamins have the potential to markedly enhance both physical and mental well-being when taken consistently.
Users have reported positive experiences when combining B-Complex vitamins with other supplements to support cardiovascular health. Many reviews highlight that these vitamins can enhance the effects of additional supplements, such as Omega 369, which is known for its cardiovascular benefits. One user specifically noted that the B-Complex, along with Omega supplements, contributes significantly to overall cardiovascular wellness by helping to lower the risk of coronary heart disease and providing essential oils for heart health Read Review. Furthermore, the synergy of B vitamins is mentioned as being effective for enhancing overall health, thereby supporting the cardiovascular system while alleviating symptoms like fatigue and stress Read Review.
Overall, users suggest that combining B-Complex vitamins with complementary supplements can result in improved energy levels, better emotional stability, and enhanced cardiovascular support. The evidence from several reviews emphasizes their collective benefit, particularly during stressful times or when experiencing vitamin deficiencies Read Review. Many have noted that consistent use leads to significant improvements in health, especially regarding cardiovascular and nervous system support, making them a powerful duo when taken in conjunction with other supplements Read Review.
Users commonly report that a single capsule of Vitamin B Complex with meals is sufficient for supporting cardiovascular health and overall well-being. Several reviewers emphasized the effectiveness of this dosage, noting improvements in energy levels, emotional stability, and cardiovascular support after starting the supplement. For instance, one user mentioned that they experienced significant decreases in stress and an overall boost in cardiovascular and nervous system health with just one capsule daily Read Review.
Others have highlighted the nutritional importance of B vitamins, suggesting that insufficient intake can lead to fatigue and poor cardiovascular health Read Review. Many users express a renewed sense of vitality and stability after incorporating B Complex into their routine, associating it with improved physical and mental health during stressful periods Read Review. Overall, while specific dosage needs can vary, reviews suggest that one capsule a day is often effective for most users seeking support for cardiovascular disease and general well-being.
7.5
Enhanced mood stability
3 people found this helpful
After starting this complex, my joint pain and depressive feelings have lessened. I noticed changes within a week, feeling more energetic and stable emotionally. This Solgar vitamin B supports my cardiovascular health and nervous system, and I appreciate its mild taste and high quality.
7.5
Improved energy levels
10 people found this helpful
I'm pleased to find this in capsule form by Solgar, which is known for quality. Since taking these vitamins, my constant fatigue has disappeared, my sleep has improved, and my hair no longer falls out. I feel my heart is healthier, and skin irritations have vanished. These vitamins are essential for my body during stressful times.
7
Supports nervous system
1 people found this helpful
I take B vitamins for my nervous system and cardiovascular health. I appreciate the positive effects I’ve experienced since starting this supplement.
9
Essential vitamin support
Founded in 1947, this B-Complex supports energy metabolism and helps manage the stresses of daily life. The individual B vitamins’re critical for maintaining healthy metabolism, particularly addressing cardiovascular disease.
9
Reduced migraine symptoms
18 people found this helpful
Trims my migraine attacks significantly. I have a classic migraine and was sceptical about B-Complex being effective, but the results were striking: my seizure frequency dropped. When I stopped taking it, my attacks increased. With this complex, I consume one pack of triptans a month instead of six to seven.
9
Improved resilience
Excellent! I’ve witnessed an increase in stress resistance and overall support for my cardiovascular and nervous system.
7.5
Supports cardiovascular health
Omega 369 is essential for cardiovascular health, formulated with beneficial oils. Research indicates omega-3s might lower coronary heart disease risk, making this a valuable addition to my daily regimen.
7.5
Boosted immune system
1 people found this helpful
B vitamins are vital for energy, emotional health, and multiple bodily functions including combatting cardiovascular disease. Insufficient B vitamins can lead to fatigue and poor memory. The synergy of this complex is effective for enhancing overall health.
7.5
High bioavailability
I recommend this vitamin complex for its bioavailability and effective absorption. It’s beneficial during periods of vitamin deficiency and supports cardiovascular disease, and I find it easy on my stomach with an affordable price.
8
Effective stress relief
1 people found this helpful
This is a high-quality complex supporting cardiovascular health and energy. It effectively relieves irritability and stress. One capsule with meals suffices, and despite their water-soluble nature, I notice improved appetite and skin condition without any adverse effects on my body.
7
Vitamin B influence on hypertension
Relationship between blood pressure variability and vitamin B level in essential hypertension.
We investigated the connection between blood pressure variability (BPV) and vitamin B6 and B12 levels in individuals with essential hypertension. Our study involved 100 patients with hypertension and a control group of 100 healthy individuals.
We found that patients with hypertension had significantly lower levels of these B vitamins compared to the healthy group. Additionally, those with higher B vitamin levels exhibited reduced BPV.
This suggests that Vitamin B6 and B12 may influence blood pressure control, providing insights into hypertension management strategies.
9
Vitamin B6 aids heart recovery
Vitamin B6 allosterically activates AMPK to promote postischemic angiogenesis in mice.
We investigated how vitamin B6 supports heart recovery after heart attacks by promoting new blood vessel growth, known as angiogenesis. In laboratory tests, vitamin B6 improved cell migration and tubule formation, vital for forming new blood vessels.
Remarkably, long-term vitamin B6 supplementation showed significant improvements in heart function and reduced inflammation in mice following heart attacks. This suggests that vitamin B6 could be a beneficial aid for heart recovery, harnessing a specific pathway involving a protein called AMPK.
8
Folate slows artery thickness increase
Serum folate levels, but not vitamin B12, are associated with slower progression in carotid intima-media thickness in a population exposed to mandatory folic acid fortification.
We examined the link between folate and vitamin B12 levels and changes in carotid intima-media thickness (cIMT), a marker of early heart disease, over eight years in a group of 5061 adults in Brazil.
Our results suggest that higher serum folate levels are associated with a slower increase in cIMT, indicating a potential protective effect against heart disease.
However, no such benefit was observed with vitamin B12 levels. This implies that while folate may play a role in cardiovascular health, vitamin B12 might not have the same impact.
8
Niacin intake lowers mortality risks
Association of dietary niacin intake with all-cause and cardiovascular mortality: National Health and Nutrition Examination Survey (NHANES) 2003-2018.
We looked into how dietary niacin might affect mortality rates, particularly for cardiovascular disease. Analyzing data from nearly 27,000 U.S. adults over about nine years, we found that those with the highest niacin intake had a significantly lower risk of dying from any cause, as well as from heart-related issues.
Interestingly, this protective effect was more robust among those without diabetes, suggesting that niacin's benefits can vary by health condition. Our findings highlight the potential role of diet in supporting heart health.
References
Bian XY, Cui C, Zhang QY. Relationship between blood pressure variability and vitamin B level in essential hypertension. J Physiol Pharmacol. 2025;76. doi:10.26402/jpp.2025.1.02
Wang XQ, Yin S, Wang QW, Bai WW, Tan RH, et al. Vitamin B6 allosterically activates AMPK to promote postischemic angiogenesis in mice. Eur J Pharmacol. 2025;993:177413. doi:10.1016/j.ejphar.2025.177413
Song Y, Choi JE, Park JM, Kwon YJ, Hong KW, et al. Genome-Wide Approach of Gene-Nutrient Intake Interaction Study for Essential Hypertension in a Large Korean Cohort (KoGES). Nutrients. 2024;16. doi:10.3390/nu16234147
Palchetti CZ, Gonçalves NG, Suemoto CK, Santos IS, Lotufo PA, et al. Serum folate levels, but not vitamin B12, are associated with slower progression in carotid intima-media thickness in a population exposed to mandatory folic acid fortification. Clin Nutr ESPEN. 2025;65:144. doi:10.1016/j.clnesp.2024.11.034
Lin L, Chen S, Zhang C, Li L, Chen Y, et al. Association of dietary niacin intake with all-cause and cardiovascular mortality: National Health and Nutrition Examination Survey (NHANES) 2003-2018. Sci Rep. 2024;14:28313. doi:10.1038/s41598-024-79986-9